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nonlinear multipurpose curvefitting program  (GraphPad Software Inc)


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    GraphPad Software Inc nonlinear multipurpose curvefitting program
    Nonlinear Multipurpose Curvefitting Program, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nonlinear+program+curvefitting+program/non+linear+regression+analysis/pm34935253-82-7-10
    Average 90 stars, based on 1 article reviews
    nonlinear multipurpose curvefitting program - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Software:

    Article Title: Functional characterization of 21 CYP3A4 variants on amiodarone metabolism in vitro.
    Article Snippet: Cytochrome P450 3A4 (CYP3A4) is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants reported previously.. Genetic polymorphisms of CYP3A4 can produce a significantly effect on the efficacy and safety of some drugs, so the purpose of this study was to clarify the catalytic characteristics of 22 CYP3A4 allelic isoforms, including 6 novel variants in Han Chinese population, on the oxidative metabolism of amiodarone in vitro.. Ac ce pt ed M an us cr ipt 2.

    Article Title: Preclinical evaluation of (S)-[ 18 F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971.
    Article Snippet: Briefly, aliquots of membrane suspension obtained from individual genotyped human brain tissue from both high affinity binders (HABs) and low affinity binders (LABs) (n = 7 each) was incubated with [3H]PK11195 (2 nM) and unlabelled (S)GE387 (10 concentrations ranging from 0.1 nM to 3 μM, in triplicate) at room temperature for 60 min. At the end of the incubation period, the suspension was filtered and washed, and the individual filter papers placed in vials before adding scintillation fluid (Perkin Elmer Ultima Gold MV) and counting in a Perkin Elmer MicroBeta Trilux liquid scintillation counter after a minimum of 30 min of being in darkness. .. The competition binding data was analysed using the iterative nonlinear regression curvefitting software supplied with GraphPad Prism 5.0. ..

    other:

    Article Title: Synthesis and biological evaluation of [ 18 F](2S,4S)4-(3-fluoropropyl) arginine as a tumor imaging agent.
    Article Snippet: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record.. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article.. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

    Article Title: Laminaria japonica cyclic peptides exert anti-colorectal carcinoma effects through apoptosis induction in vitro and in vivo.
    Article Snippet: Jie Liu, State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University Health Science Center, Shenzhen 518060, China.. Email: liujieszu@163.com Laminaria japonica is consumed as a health food and used as a traditional medicine because of its biochemical and pharmacological abilities.. However, the anti-tumor effect of L. japonica peptides has not been well explored.

    Article Title: Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus.
    Article Snippet: Here, we described the effects of obesity induced by high-calorie diet and its treatment with exenatide, an antidiabetogenic and potential anti-obesogenic drug derived from the venom of the Gila monster Heloderma suspectum, on the affinity, density, subtypes and intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors (mAChRs) in rat hippocampus.. Male Wistar rats were divided into three groups: control (CT), obese induced by high-calorie diet (DIO) and DIO treated with exenatide (DIO+E).. [H]Quinuclidinyl benzilate specific binding analysis showed that the equilibrium dissociation constant (KD) did not differ among CT, DIO and DIO+E, indicating that affinity is not affected by high-calorie diet or its treatment with exenatide.

    Binding Assay:

    Article Title: Preclinical evaluation of (S)-[ 18 F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971.
    Article Snippet: Briefly, aliquots of membrane suspension obtained from individual genotyped human brain tissue from both high affinity binders (HABs) and low affinity binders (LABs) (n = 7 each) was incubated with [3H]PK11195 (2 nM) and unlabelled (S)GE387 (10 concentrations ranging from 0.1 nM to 3 μM, in triplicate) at room temperature for 60 min. At the end of the incubation period, the suspension was filtered and washed, and the individual filter papers placed in vials before adding scintillation fluid (Perkin Elmer Ultima Gold MV) and counting in a Perkin Elmer MicroBeta Trilux liquid scintillation counter after a minimum of 30 min of being in darkness. .. The competition binding data was analysed using the iterative nonlinear regression curvefitting software supplied with GraphPad Prism 5.0. ..



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